Detection of fentanyl and derivatives using a lateral flow immunoassay

Overdoses due to the adulteration of illegal opioid drug supply with synthetic opioids (i.e. fentanyl and derivatives) continue be a serious problem in United States. The presence these substances this not only presents risk users, but also first responders. Synthetic have high toxicity leads overdose or accidental exposure when they are included supply. Due toxicity, responders forensic scientists need for rapid, accurate, low-cost detection methods. In study, we examined commercially available fentanyl-directed lateral flow immunoassay (LFI) produced by BTNX, Inc. (Markham, ON Canada). Several aspects performance were examined: limits (LODs) sensitivity derivatives liquid from dried surface sampled fentanyl, effectiveness complex illicit street samples, as well ability LFIs determine vivo urine rabbits human collected postmortem cases. results study suggest that potential used both field.